Several blood thinners are affected by grapefruit. This can lead to bleeding or less effective prevention of blood clots. Fentanyl and oxycodone are narcotic pain relievers. Although their blood levels are only slightly affected by small amounts of grapefruit, it may change the length of time they remain in the body 16 , Colchicine is an older medication used to treat gout.
Nevertheless, a study showed that drinking mL of grapefruit juice only had a minimal effect on its levels Alternatives: Morphine and Dilaudid are narcotic pain relievers that are not affected by grapefruit 1.
A few erectile dysfunction and prostate medications deserve attention regarding grapefruit interactions:. Erectile dysfunction medications like sildenafil and tadalafil work by relaxing blood vessels, which increases blood flow to an erection.
Because other blood vessels relax with these medications as well, increased blood levels of these drugs caused by grapefruit can decrease blood pressure 8. Moreover, prostate enlargement medications such as tamsulosin can also cause increased dizziness and low blood pressure when taken with grapefruit Alternatives: Another class of prostate enlargement medications, which includes finasteride and dutasteride, is not significantly affected by grapefruit Grapefruit should not be consumed with erectile dysfunction medications or certain prostate enlargement medications.
Additionally, Rxlist. And some of these medications may have serious side effects when they interact with grapefruit. If you are currently taking medications with grapefruit interactions, switch to an alternative drug or stop consuming grapefruit. Even small amounts of grapefruit can interact with some medications and cause serious side effects. Grapefruit interferes with proteins in the small intestine and liver that normally break down many medications.
Eating grapefruit or drinking grapefruit juice while taking these medications can lead to higher levels of them in your blood — and more side effects. With some drugs, with even small amounts of grapefruit can cause severe side effects. Therefore, the combination should be avoided. Make sure your doctor and pharmacist know if you regularly consume grapefruit. Grapefruit can affect how fast some drugs — like statins — are absorbed into the bloodstream.
These include many drugs used to treat blood vessel and…. Is it safe to have grapefruit and metformin together? We'll tell you what the research says. Grapefruits are known to interact with dozens of medicines, including birth control pills. The list of medications that can interact with grapefruit includes commonly prescribed medications that:. Another potential problem is that some foods and drinks may contain grapefruit but don't say so in the name or on the ingredients list.
For example, numerous citrus-flavored soft drinks contain grapefruit juice or grapefruit extract. Play it safe with prescription drugs. Always ask your doctor or pharmacist when you get a new prescription if it interacts with any foods or other medicines.
If the answer is yes, ask whether you need to eliminate that food from your diet. Katherine Zeratsky, R. There is a problem with information submitted for this request.
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Our Housecall e-newsletter will keep you up-to-date on the latest health information. Mayo Clinic does not endorse companies or products. The clinical information is incomplete, but men who take Viagra should be aware that grapefruit juice might boost blood levels of the drug. That could be a good thing for some men with erectile dysfunction, but it could trigger headaches, flushing, or low blood pressure.
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Get helpful tips and guidance for everything from fighting inflammation to finding the best diets for weight loss Stay on top of latest health news from Harvard Medical School. Recent Blog Articles. Why is topical vitamin C important for skin health? Preventing preeclampsia may be as simple as taking an aspirin. Caring for an aging parent? Eating grapefruit or drinking grapefruit juice can affect some medicines. In most cases, it increases the level of the medicine in your blood.
This can increase the risk of side effects or change the effect the medicine has. If your usual diet includes grapefruit or grapefruit juice and you've been prescribed a medicine that's affected by grapefruit, speak to your GP or pharmacist.
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